BIOL 8070 Viruses and Evolution Theory (Fall: 2 )
Viruses are adept at exploring sequence space and exploiting a wide variety of adaptive strategies, resulting in an extensive assortment of genome architectures. For these reasons, viruses have long served as important model systems for understanding and testing evolutionary theory. In addition, many important aspects of viruses – such as adaptation to host cells, virulence, pathogenesis, transmission within and between populations, and their impact on organismal ecology and evolution – are best understood within the framework of population genetics and evolutionary theory. In this course, we will draw on the primary virological literature to explore important concepts in evolutionary biology, such as: viruses and the origins of life; quasispecies theory; robustness, cryptic variation, and the balance between stability and evolvability; and the relationship between genome architecture and information content.
Instructor(s): Jamie Henzy and Welkin Johnson
Last Updated: 29-Apr-14